Aging is an inevitable process that affects every cell in the body, leading to decreased function, increased disease risk, and eventual decline. Scientists have long hoped to reverse this decline, inspired by results like exposing old animals to young blood (parabiosis) or using powerful gene…
Senescence, the process where cells permanently stop dividing, has long puzzled cancer researchers: it can suppress tumors by halting uncontrolled growth, yet in some contexts it fuels cancer progression by altering the surrounding environment. This paradox is especially relevant in lung…
In the ongoing battle against Alzheimer’s Disease (AD), where innovative research is key to unlocking new treatments, a recent grant from the Cure Alzheimer’s Fund to postdoctoral researcher Jarin Tusnim stands out.
A recent study published in ASCB – Molecular Biology of the Cell by Diane Barber and her BARI team introduces a practical new model for investigating frontotemporal dementia (FTD), a neurodegenerative disorder that pri
A recent study published in Science by Diana Laird and her BARI team presents the most comprehensive single-cell atlas of aging ovaries in humans and mice to date.
A recent article in the American Journal of Transplantation from researchers at the BARI, led by John Greenland and team, explores the biological underpinnings of how frailty, a state of increased vulnerab
Alzheimer’s disease (AD) is one of the most common causes of dementia in older adults, marked by memory loss and cognitive decline. Despite that microglia are known to surround toxic amyloid-beta plaques and exhibit a protective role, the exact mechanism by which microglia shift to a protective…
The ‘Silent’ X Chromosome Gives the Aging Female Brain a BoostIn a surprise, work in mice has found that the dormant X chromosome in females can reawaken late in life and turn on genes that keep the brain healthy.
